UNIQUE MODELS OF CARDIOVASCULAR FUNCTION
The human species only contains so much variability in physiological function, but the animal kingdom provides many insights into unique adaptations to what might be considered pathology in humans. We partner with species experts to understand how these adaptations lead to their unique physiology at the molecular level. The work spans from tool/reference building to high resolution molecular profiling using short and long read technologies.
A beary good genome: Haplotype-resolved, chromosome-level assembly of the brown bear (Ursus arctos). Ellie E. Armstrong, Blair W. Perry, Yongqing Huang, Kiran V. Garimella, Heiko T. Jansen, Charles T. Robbins, Nathan R. Tucker,* Joanna L. Kelley* bioRxiv 2022.06.17.496447